2025 Home Run Derby Odds: Oneil Cruz, Cal Raleigh Top Favorites

The 2025 MLB Home Run Derby is set to electrify Truist Park in Atlanta on Monday, July 14, showcasing a fresh slate of contenders ready to take center stage in baseball’s ultimate power showdown.

This year’s lineup excludes last year’s competitors, opening the door for a new wave of stars including James Wood, Junior Caminero, Byron Buxton, Brent Rooker, Ronald Acuna Jr., Jazz Chisholm, Cal Raleigh, and the current odds favorite, Oneil Cruz.

Despite not cracking the top tier of regular-season home run hitters, Pittsburgh’s Oneil Cruz heads into the Derby as the frontrunner with +333 odds on BetMGM. Cruz, who currently sports a .204 batting average and 16 home runs, has a reputation for crushing the baseball with exceptional exit velocity. His May 25 blast, which left the bat at 122.9 mph, stands as the hardest-hit home run in Statcast history. His elite power potential and ability to barrel pitches make him a prime candidate in a format designed for slugging.

Seattle Mariners catcher Cal Raleigh sits just behind Cruz at +360. Raleigh leads Major League Baseball with 36 home runs as of July 11 and is having a breakout season. He’s already surpassed his 2024 total of 34 homers in just 336 at-bats. His consistent power display positions him as a major threat to capture the Derby crown.

Ronald Acuna Jr., who returned from injury in late May and has 11 home runs so far, holds +400 odds. Benefiting from the support of the home crowd in Atlanta, Acuna could deliver a strong performance on familiar turf.

Emerging names like James Wood (24 HRs), Junior Caminero, and Byron Buxton follow closely in the odds, while Jazz Chisholm, the New York Yankees’ infielder, enters with the longest shot at 13-1.

2025 Home Run Derby Odds

  • Cal Raleigh: +152
  • Oneil Cruz: +154
  • Ronald Acuna Jr.: +198
  • James Wood: +260
  • Byron Buxton: +370
  • Junior Caminero: +440
  • Brent Rooker: +490
  • Jazz Chisholm: +490

At BetMGM, James Wood has drawn the highest percentage of bets (18%) and total money wagered (34.4%), making him the book’s biggest liability heading into the event.

Cruz is +1200 to defeat Raleigh in the final, while Raleigh beating Cruz holds +1400 odds — suggesting a potential final-round matchup between the power-packed duo.

With no former champions in the bracket, this year’s competition promises unpredictability and fireworks, setting the stage for a new home run king to rise in Atlanta.